Sex-specific differences in cardiac transthyretin amyloidosis: addressing the diagnostic gap in women
Transthyretin amyloid cardiomyopathy presents with persistent sex-specific differences that may contribute to diagnostic delay in women. Current diagnostic thresholds may not adequately reflect female disease patterns, underscoring the need for sex-adapted diagnostic criteria to improve early detection and management.
Authors
- Stephan Settelmeier
- Alexander Carpinteiro (ORCID: https://orcid.org/0000-0002-3316-9166)
- T Rassaf
- Judith Vogel
- Tobias Lerchner (ORCID: https://orcid.org/0000-0003-1120-4087)
- L Yahsaly
- Florian Buehning
- Lars Michel (ORCID: https://orcid.org/0009-0002-6122-5652)
- Sophia Jura
- H Christian Reinhardt
Institutions
- Essen University Hospital (DE)
- West German Heart and Vascular Center Essen (DE)
Publication Details
- Journal
- European Heart Journal Open
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1093/ehjopen/oeaf175
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00