The Distinct Monocyte Subsets and Intercellular Communication in Primary Sjögren's Syndrome Revealed by Single-Cell RNA Sequencing

This research revealed irregular alterations in monocyte subsets and sub-populations, transcription factors, and gene expression patterns within pSS patients, pinpointing prospective biomarkers in pSS as viable targets for therapeutic intervention.

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Publication Details

Journal
Journal of Clinical Immunology
Published
2025-12-27
DOI
https://doi.org/10.1007/s10875-025-01974-z
Primary Topic
Salivary Gland Disorders and Functions
Type
article
Field-Weighted Citation Impact
0.00
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article

The Distinct Monocyte Subsets and Intercellular Communication in Primary Sjögren's Syndrome Revealed by Single-Cell RNA Sequencing

Bo Zang, B Liu, Xiaoyu Zhang, Yifei Yang et al.
Journal of Clinical Immunology
Salivary Gland Disorders and Functions
article

The Distinct Monocyte Subsets and Intercellular Communication in Primary Sjögren's Syndrome Revealed by Single-Cell RNA Sequencing

Bo Zang, B Liu, Xiaoyu Zhang, Yifei Yang, QiXuan Liu, Xiangrong Song, Yuanwei Han, Jiaxiu Li, Meng Xu, Hong Zhu, Li Fang
article en

Abstract

This research revealed irregular alterations in monocyte subsets and sub-populations, transcription factors, and gene expression patterns within pSS patients, pinpointing prospective biomarkers in pSS as viable targets for therapeutic intervention.

Journal of Clinical ImmunologyVol. 46(1)
Qingdao University (CN), Affiliated Hospital of Qingdao University (CN), Ningxia Medical University (CN), Ningxia Water Conservancy (CN), Ningxia Medical University General Hospital (CN), Yueqing People's Hospital (CN), University of California, Davis (US)
Good health and well-being
Openalex Percentile: Top 32%
Salivary Gland Disorders and Functions
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