Renal Function Outcomes in Tuberous Sclerosis Complex Patients Receiving Everolimus for Renal Angiomyolipoma

In this study, we evaluated kidney function in patients with renal angiomyolipoma associated with tuberous sclerosis complex (TSC-RAML), who received everolimus treatment. We found that kidney function was generally stable and even improved in patients with marked tumor reduction. These results suggest that everolimus may help preserve or enhance kidney health in selected patients with TSC-RAML.

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Publication Details

Journal
European Urology Open Science
Published
2025-12-27
DOI
https://doi.org/10.1016/j.euros.2025.12.013
Primary Topic
Tuberous Sclerosis Complex Research
Type
article
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article

Renal Function Outcomes in Tuberous Sclerosis Complex Patients Receiving Everolimus for Renal Angiomyolipoma

Yushi Zhang, Dongxu Qiu, Yang Zhao, Zhangcheng Liao et al.
European Urology Open Science
Tuberous Sclerosis Complex Research
article

Renal Function Outcomes in Tuberous Sclerosis Complex Patients Receiving Everolimus for Renal Angiomyolipoma

Yushi Zhang, Dongxu Qiu, Yang Zhao, Zhangcheng Liao, Wenda Wang, Yi Liu
article en

Abstract

In this study, we evaluated kidney function in patients with renal angiomyolipoma associated with tuberous sclerosis complex (TSC-RAML), who received everolimus treatment. We found that kidney function was generally stable and even improved in patients with marked tumor reduction. These results suggest that everolimus may help preserve or enhance kidney health in selected patients with TSC-RAML.

European Urology Open ScienceVol. 83
Central South University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN), Xiangya Hospital Central South University (CN)
Good health and well-being
Openalex Percentile: Top 32%
Tuberous Sclerosis Complex Research
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