Optimizing kappa free light chain index thresholds for multiple sclerosis (MS) diagnosis in low-MS prevalence regions: Insights from an Asian cohort

The KFLC index is a reliable biomarker for MS diagnosis in Asian populations. Optimized and sex-specific thresholds may enhance diagnostic precision where MS mimics are relatively prevalent, consistent with diagnostic performance globally.

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Publication Details

Journal
Multiple Sclerosis Journal
Published
2025-12-27
DOI
https://doi.org/10.1177/13524585251399102
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
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article

Optimizing kappa free light chain index thresholds for multiple sclerosis (MS) diagnosis in low-MS prevalence regions: Insights from an Asian cohort

Minji Joo, Rosah May Palermo Payumo, Jieun Chung, Ki Hoon Kim et al.
Multiple Sclerosis Journal
Multiple Sclerosis Research Studies
article

Optimizing kappa free light chain index thresholds for multiple sclerosis (MS) diagnosis in low-MS prevalence regions: Insights from an Asian cohort

Minji Joo, Rosah May Palermo Payumo, Jieun Chung, Ki Hoon Kim, Jae-Won Hyun, You-Ri Kang, Ho Jin Kim, Su-Hyun Kim
article en

Abstract

The KFLC index is a reliable biomarker for MS diagnosis in Asian populations. Optimized and sex-specific thresholds may enhance diagnostic precision where MS mimics are relatively prevalent, consistent with diagnostic performance globally.

Multiple Sclerosis JournalVol. 32(2)
Yonsei University (KR), Severance Hospital (KR), National Cancer Center (US), Chonnam National University Hospital (KR), National Cancer Center (KR)
Openalex Percentile: Top 29%
Multiple Sclerosis Research Studies
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Optimizing kappa free light chain index thresholds for multiple sclerosis (MS) diagnosis in low-MS prevalence regions: Insights from an Asian cohort — Minji Joo, Rosah May Palermo Payumo, et al. · Multiple Sclerosis Journal (2025) | TGRS Research Map | TGRS