Comparison of Different Side Branch Ballooning Following Provisional Stenting in Coronary Bifurcation Lesion-Related STEMI

The present study retrospectively assessed clinical outcomes of proximal optimization technique (POT)-kissing-POT (PKP) and POT-side-POT (PSP) in ST-segment elevation myocardial infarction (STEMI) patients with culprit coronary bifurcation lesion (CBL) following a provisional stenting (PS). This large-scale multicenter (n = 10) study included STEMI patients with culprit CBLs who underwent PKP or PSP following PS. The primary endpoint was defined as the major adverse cardiac events (MACE; cardiac death, target vessel myocardial infarction [TVMI], or clinically driven target lesion revascularization [TLR]). Consecutive patients (n = 596; male: 491 [82.3%], mean age: 58.1 ± 11.7 years) were included. The study cohort was divided into 2 groups: PKP (n = 386) and PSP (n = 210). In the overall population, mid-term MACE (hazard ratio [HR]: 0.921, <i>P</i> = .461) did not differ in individuals with CBL-related STEMI treated with either PKP or PSP. The frequency of main vessel-TLR (0% vs 30%, <i>P</i> = .001) and main vessel-TVMI (0% vs 20%, <i>P</i> = .014) were significantly lower in the PKP group in the left main bifurcation localization. Diabetes mellitus (HR: 2.628, <i>P</i> < .001), high SYNTAX score (HR: 1.081, <i>P</i> < .001), and bifurcation localization (HR: 2.109, <i>P</i> = .014) were found to be independent predictors of MACE. In the overall population, risk-adjusted MACE rates for culprit CBLs were comparable between both techniques.

Authors

Institutions

Publication Details

Journal
Angiology
Published
2025-12-27
DOI
https://doi.org/10.1177/00033197251390099
Primary Topic
Coronary Interventions and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Comparison of Different Side Branch Ballooning Following Provisional Stenting in Coronary Bifurcation Lesion-Related STEMI

Hande Uysal, Ziya Apaydın, Hicaz Zencirkıran Ağuş, Adnan Özel et al.
Angiology
Coronary Interventions and Diagnostics
article

Comparison of Different Side Branch Ballooning Following Provisional Stenting in Coronary Bifurcation Lesion-Related STEMI

Hande Uysal, Ziya Apaydın, Hicaz Zencirkıran Ağuş, Adnan Özel, Barış Şimşek, Fatih Uzun, Emre Paçacı, Ahmet Öz, Koray Demirci, Veysel Ozan Tanık, Ali Kılınç, Ahmet Arif Yalçın, Ebru Serin, Azmican Kaya, Kaan Gökçe, Esin Karakaya, Ali Nural, Sinem Çakal, Mehmet Akif Erdöl, Abdullah Kadir Dolu, Büşra Çörekçioğlu, Koray Çiloğlu, Berkay Serter, Ahmet Ceyhun Cebeci, Ahmet Öztürk, Abdullah Doğan, Ezgi Gültekin Güner, Fatih Furkan Bedir, Mustafa Kamil Yemiş, Ezgi Merve Çelik, Aybüke Şimşek, Saner Bahadır Gök, Yusuf Yiğit Yılmaz, Regayip Zehir, Mustafa Sarı, Mustafa Ferhat Keten, Kudret Keskin, Cemalettin Akman, Mert Evlice, Ahmet Güner
article en

Abstract

The present study retrospectively assessed clinical outcomes of proximal optimization technique (POT)-kissing-POT (PKP) and POT-side-POT (PSP) in ST-segment elevation myocardial infarction (STEMI) patients with culprit coronary bifurcation lesion (CBL) following a provisional stenting (PS). This large-scale multicenter (n = 10) study included STEMI patients with culprit CBLs who underwent PKP or PSP following PS. The primary endpoint was defined as the major adverse cardiac events (MACE; cardiac death, target vessel myocardial infarction [TVMI], or clinically driven target lesion revascularization [TLR]). Consecutive patients (n = 596; male: 491 [82.3%], mean age: 58.1 ± 11.7 years) were included. The study cohort was divided into 2 groups: PKP (n = 386) and PSP (n = 210). In the overall population, mid-term MACE (hazard ratio [HR]: 0.921, <i>P</i> = .461) did not differ in individuals with CBL-related STEMI treated with either PKP or PSP. The frequency of main vessel-TLR (0% vs 30%, <i>P</i> = .001) and main vessel-TVMI (0% vs 20%, <i>P</i> = .014) were significantly lower in the PKP group in the left main bifurcation localization. Diabetes mellitus (HR: 2.628, <i>P</i> < .001), high SYNTAX score (HR: 1.081, <i>P</i> < .001), and bifurcation localization (HR: 2.109, <i>P</i> = .014) were found to be independent predictors of MACE. In the overall population, risk-adjusted MACE rates for culprit CBLs were comparable between both techniques.

Angiology
Adıyaman University (TR), Izmir Kâtip Çelebi University (TR), Turkish Armed Forces (TR), Memorial Ankara Hospital (TR), Haseki Eğitim ve Araştırma Hastanesi (TR), Education Training And Research (US), Sağlık Bilimleri Üniversitesi (TR), Kartal Koşuyolu High Specialization Training and Research Hospital (TR), Turku City Hospital (FI), Şişli Etfal Eğitim ve Araştırma Hastanesi (TR), Dr. Siyami Ersek Göğüs Kalp Ve Damar Cerrahisi Eğitim Ve Araştırma Hastanesi (TR), Burdur Mehmet Akif Ersoy Üniversitesi (TR)
Good health and well-being
Openalex Percentile: Top 26%
Coronary Interventions and Diagnostics
DOISourceOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.