Osteocyte-Intrinsic MMP13 exacerbates injury-induced temporomandibular joint osteoarthritis
Despite different roles for osteocytic MMP13 in TMJ and knee, osteocytic MMP13 deficiency protects both joints from injury-dependent effects on subchondral bone.
Authors
- Harrison Taylor
- Alena D. Larios
- Peggi M. Angel (ORCID: https://orcid.org/0000-0002-4436-555X)
- Karsyn N. Bailey (ORCID: https://orcid.org/0000-0002-0581-2839)
- Marianne Demirdji
- Tamara Alliston
- Cristal S. Yee
- Sunil D. Kapila
- Clarissa Aguirre Luna
- Christoforos Meliadis
Institutions
- Medical University of South Carolina (US)
- University of California, Los Angeles (US)
- University of California, San Francisco (US)
- Washington University in St. Louis (US)
- University of California System (US)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (US)
Publication Details
- Journal
- Osteoarthritis and Cartilage
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.joca.2025.12.019
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical University of South Carolina
- University of Michigan
- University of South Carolina
- National Institutes of Health
- National Institute of General Medical Sciences
- National Institute of Arthritis and Musculoskeletal and Skin Diseases
- National Institute of Dental and Craniofacial Research
- National Center for Research Resources