Evaluation of salivary matrix metalloproteinase-12 levels in patients with oral lekoplakia and oral squamous cell carcinoma using enzyme-linked immunosorbent assay

MMP-12 levels in the saliva of the OSCC patients were considerably higher than in the OL and healthy controls. The salivary MMP-12 levels were higher in higher grades of epithelial dysplasia and OSCCs. Hence, salivary MMP-12 levels can be used as a non-invasive, early diagnostic and prognostic biomarker for OSCC.

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Publication Details

Journal
Journal of Oral and Maxillofacial Pathology
Published
2025-10-01
DOI
https://doi.org/10.4103/jomfp.jomfp_236_25
Primary Topic
Salivary Gland Disorders and Functions
Type
article
Field-Weighted Citation Impact
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article

Evaluation of salivary matrix metalloproteinase-12 levels in patients with oral lekoplakia and oral squamous cell carcinoma using enzyme-linked immunosorbent assay

Rathy Ravindran, P Jayanthi, S. D. Asha, T. Nripan et al.
Journal of Oral and Maxillofacial Pathology
Salivary Gland Disorders and Functions
article

Evaluation of salivary matrix metalloproteinase-12 levels in patients with oral lekoplakia and oral squamous cell carcinoma using enzyme-linked immunosorbent assay

Rathy Ravindran, P Jayanthi, S. D. Asha, T. Nripan, Manasa M. Babu
article en

Abstract

MMP-12 levels in the saliva of the OSCC patients were considerably higher than in the OL and healthy controls. The salivary MMP-12 levels were higher in higher grades of epithelial dysplasia and OSCCs. Hence, salivary MMP-12 levels can be used as a non-invasive, early diagnostic and prognostic biomarker for OSCC.

Journal of Oral and Maxillofacial PathologyVol. 29(4)
Noorul Islam College of Dental Science (IN)
Openalex Percentile: Top 32%
Salivary Gland Disorders and Functions
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