Wearable Laser Doppler Flowmetry and Fluorescence Spectroscopy Devices: Instrumentation and Methodology of Application in Clinical and Space Research

The work aims to study the latest technical developments in instrumental support of laser Doppler flowmetry (LDF) and fluorescence spectroscopy (FS) methods and to evaluate the possibilities of using wearable LDF and FS devices in clinical practice and space medicine. The paper demonstrates the principle of the implementation of wearable LDF and FS devices, the possibilities of forming distributed analyser systems for simultaneous registration of parameters in several areas of interest, and demonstrates examples of registered signals. Prospects and directions of device application in clinical practice are estimated. For the first time, research was conducted to demonstrate the possibility of using wearable LDF and FS devices to record physiological parameters of astronauts in real time during pre-flight training with exposure to overloads, hypoxia and hypobaria, orthostatic and vestibular effects.