Autophagy related 7 dysfunction in senescent melanocytes and hypopigmented skin: reversal by metformin
Early autophagy dysfunction represents a key initiating event in melanocyte senescence. Autophagy preservation particularly through ATG7 maintenance offers a promising early intervention strategy to prevent melanocyte aging and related hypopigmentary disorders.
Authors
- Yeongeun Kim (ORCID: https://orcid.org/0000-0002-6113-1253)
- Hee Young KANG
- Jin Cheol Kim (ORCID: https://orcid.org/0000-0003-3820-8811)
- So Yeon Myeong
- Hyun Jung Kim (ORCID: https://orcid.org/0000-0001-5342-2870)
- Tae Jun Park
- Hoyeon Choi
Institutions
- Gachon University (KR)
- Ajou University (KR)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1093/bjd/ljaf529
- Citations
- 1
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 1.16