Neuroprotective Effects of Dapagliflozin on Hippocampal Adult Neurogenesis and Synaptic Integrity in Rats with Doxorubicin‐induced Chemobrain
Our findings indicate that doxorubicin induces chemobrain, as shown by impairments in adult neurogenesis and synaptic integrity. Dapagliflozin mitigates the chemobrain induced by doxorubicin. Thus, dapagliflozin may serve as a therapeutic approach to alleviate chemobrain induced by doxorubicin.
Authors
- Busarin Arunsak (ORCID: https://orcid.org/0000-0002-5120-288X)
- Patcharapong Pantiya (ORCID: https://orcid.org/0000-0002-2181-7197)
- Nipon Chattipakorn
- Chayadom Maneechote
- Titikorn Chunchai
- Hiranya Pintana
- Siriporn C Chattipakorn
Institutions
- Chiang Mai University (TH)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_100062
- Primary Topic
- Cancer-related cognitive impairment studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00