Groin Soft Tissue Leiomyosarcoma or Femoral Vein Leiomyosarcoma?

Leiomyosarcoma is a rare, poorly studied malignancy derived from smooth muscle cells, prone to recurrence and metastasis. Of superficial neoplasms, soft tissue leiomyosarcomas account for no more than 2.3%, while tumors of vascular origin, which mainly occur in large veins, account for 0.5% to 0.7% of cases. In the practice of a vascular surgeon or phlebologist, patients often have a combined pathology of the lower extremities (chronic venous disease, atherosclerotic obliterans of the lower extremity arteries, varicose disease, gonarthrosis, etc.). The article presents a clinical case of soft tissue leiomyosarcoma of the inguinal region in a patient treated for the left lower extremity varicose vein disease shortly before the detection of a tumor. The possibility that any physician may encounter a patient in need of treatment for a rare malignancy such as soft tissue leiomyosarcoma has been shown.

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Publication Details

Journal
Journal of Venous Disorders
Published
2025-12-27
DOI
https://doi.org/10.17116/flebo202519041316
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
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article

Groin Soft Tissue Leiomyosarcoma or Femoral Vein Leiomyosarcoma?

S.A. Zvezda, D.M. Aminov, L. N. Komarova, O.V. Tikhonenkova
Journal of Venous Disorders
Sarcoma Diagnosis and Treatment
article

Groin Soft Tissue Leiomyosarcoma or Femoral Vein Leiomyosarcoma?

S.A. Zvezda, D.M. Aminov, L. N. Komarova, O.V. Tikhonenkova
article en

Abstract

Leiomyosarcoma is a rare, poorly studied malignancy derived from smooth muscle cells, prone to recurrence and metastasis. Of superficial neoplasms, soft tissue leiomyosarcomas account for no more than 2.3%, while tumors of vascular origin, which mainly occur in large veins, account for 0.5% to 0.7% of cases. In the practice of a vascular surgeon or phlebologist, patients often have a combined pathology of the lower extremities (chronic venous disease, atherosclerotic obliterans of the lower extremity arteries, varicose disease, gonarthrosis, etc.). The article presents a clinical case of soft tissue leiomyosarcoma of the inguinal region in a patient treated for the left lower extremity varicose vein disease shortly before the detection of a tumor. The possibility that any physician may encounter a patient in need of treatment for a rare malignancy such as soft tissue leiomyosarcoma has been shown.

Journal of Venous DisordersVol. 19(4)
Saint Petersburg State University of Aerospace and Instrumentation (RU), University of Tyumen (RU), Tyumen State Medical University (RU)
Good health and well-being
Openalex Percentile: Top 28%
Sarcoma Diagnosis and Treatment
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Groin Soft Tissue Leiomyosarcoma or Femoral Vein Leiomyosarcoma? — S.A. Zvezda, D.M. Aminov, et al. · Journal of Venous Disorders (2025) | TGRS Research Map | TGRS