PhytoIntelligence 1.8 Finalized Evidence-Based Research Proposal Project D021.1: Multi-Pathway Network Pharmacology for GBM

This finalized proposal presents the biochemical rationale for the D021.1 formulation. Each component is selected based on its Cd score and supported by contemporary scientific literature (2021–2025). The protocol utilizes Borneol-mediated BBB opening and Berberine-mediated efflux inhibition to ensure that the primary flavonol matrix (Quercetin/Cannflavins) reaches therapeutic concentrations in the CNS.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-12-26
DOI
https://doi.org/10.5281/zenodo.18062531
Primary Topic
Berberine and alkaloids research
Type
article
Field-Weighted Citation Impact
0.00
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article

PhytoIntelligence 1.8 Finalized Evidence-Based Research Proposal Project D021.1: Multi-Pathway Network Pharmacology for GBM

Marie Seshat Landry
Zenodo (CERN European Organization for Nuclear Research)
Berberine and alkaloids research
article

PhytoIntelligence 1.8 Finalized Evidence-Based Research Proposal Project D021.1: Multi-Pathway Network Pharmacology for GBM

Marie Seshat Landry
article en

Abstract

This finalized proposal presents the biochemical rationale for the D021.1 formulation. Each component is selected based on its Cd score and supported by contemporary scientific literature (2021–2025). The protocol utilizes Borneol-mediated BBB opening and Berberine-mediated efflux inhibition to ensure that the primary flavonol matrix (Quercetin/Cannflavins) reaches therapeutic concentrations in the CNS.

Zenodo (CERN European Organization for Nuclear Research)
International Society for Optics and Photonics (US)
Openalex Percentile: Top 30%
Berberine and alkaloids research
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PhytoIntelligence 1.8 Finalized Evidence-Based Research Proposal Project D021.1: Multi-Pathway Network Pharmacology for GBM — Marie Seshat Landry · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS