Effect of Enzymatic-based chemomechanical caries removal agent on proliferation and osteogenic differentiation of dental pulp stem cells
Enzymatic-based CMCR exhibits favorable biocompatibility, particularly when applied directly on DPSCs at low concentrations and when used indirectly through dentin discs. These findings suggest that this enzymatic caries removal approach is potentially safe, effective, and minimally invasive, making it suitable for conservative restorative dentistry.
Authors
- Yousry Mahmoud Elhawary (ORCID: https://orcid.org/0000-0001-7182-9551)
- Menatalla Elhindawy
- Hamdi H. Hamama (ORCID: https://orcid.org/0000-0003-3205-345X)
- Hossam Gouda
- Asmaa S. Elmahdy
Institutions
- Damietta University (EG)
- Mansoura University (EG)
- Tanta University (EG)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1186/s12903-025-07495-w
- Primary Topic
- Bone and Dental Protein Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00