Integrating Novel Metabolomics Biomarkers with Multi‐modal Risk Factors in Predicting Mild Cognitive Impairment and Alzheimer's Disease

New molecular biomarkers (from both blood and saliva) perform strongly when integrated into databases with established AD biomarkers and risk factors. Implications include (1) enhancing identification of early mechanistic pathways, (2) importance of conducting integrative and interactive biomarker analyses, especially data-driven, and (3) potential for non-invasive salivary biomarkers for promoting assessment accessibility across diverse communities.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_104500
Primary Topic
Metabolomics and Mass Spectrometry Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Integrating Novel Metabolomics Biomarkers with Multi‐modal Risk Factors in Predicting Mild Cognitive Impairment and Alzheimer's Disease

Linzy Bohn, Shannon M. Drouin, Roger A. Dixon, Liang Li et al.
Alzheimer s & Dementia
Metabolomics and Mass Spectrometry Studies
article

Integrating Novel Metabolomics Biomarkers with Multi‐modal Risk Factors in Predicting Mild Cognitive Impairment and Alzheimer's Disease

Linzy Bohn, Shannon M. Drouin, Roger A. Dixon, Liang Li, Shuang Zhao
article en

Abstract

New molecular biomarkers (from both blood and saliva) perform strongly when integrated into databases with established AD biomarkers and risk factors. Implications include (1) enhancing identification of early mechanistic pathways, (2) importance of conducting integrative and interactive biomarker analyses, especially data-driven, and (3) potential for non-invasive salivary biomarkers for promoting assessment accessibility across diverse communities.

Alzheimer s & DementiaVol. 21(S2)
University of Alberta (CA)
Openalex Percentile: Top 36%
Metabolomics and Mass Spectrometry Studies
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