The characteristics of pulmonary fibrosis in a neonatal rat model of chronic hyperoxia lung injury

Pulmonary fibrosis in chronic hyperoxia-induced lung injury emerged by P14, peaked around P21, and stabilized thereafter. These findings offer insight into the temporal dynamics of fibrosis development in BPD and may help guide timing for therapeutic intervention.

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Publication Details

Journal
Translational Pediatrics
Published
2025-12-01
DOI
https://doi.org/10.21037/tp-2025-574
Primary Topic
Neonatal Respiratory Health Research
Type
article
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article

The characteristics of pulmonary fibrosis in a neonatal rat model of chronic hyperoxia lung injury

C. Chen, H. Wu, Wei Shen, Lin Yuan
Translational Pediatrics
Neonatal Respiratory Health Research
article

The characteristics of pulmonary fibrosis in a neonatal rat model of chronic hyperoxia lung injury

C. Chen, H. Wu, Wei Shen, Lin Yuan
article en

Abstract

Pulmonary fibrosis in chronic hyperoxia-induced lung injury emerged by P14, peaked around P21, and stabilized thereafter. These findings offer insight into the temporal dynamics of fibrosis development in BPD and may help guide timing for therapeutic intervention.

Translational PediatricsVol. 14(12)
Children's Hospital of Fudan University (CN), Xiamen Maternal and Child Health Hospital (CN)
Good health and well-being
Openalex Percentile: Top 28%
Neonatal Respiratory Health Research
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The characteristics of pulmonary fibrosis in a neonatal rat model of chronic hyperoxia lung injury — C. Chen, H. Wu, et al. · Translational Pediatrics (2025) | TGRS Research Map | TGRS