Global and local information‐based prostate image registration of prostate‐specific membrane antigen PET/CT and enhanced MRI

This study presents GLNet, a deep learning-based non-rigid registration network that fuses PSMA PET/CT and contrast-enhanced MRI. GLNet outperforms existing methods in registration accuracy and lesion detection, thereby offering a promising approach for integrating structural and functional imaging in clinical PCa diagnosis.

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Publication Details

Journal
Medical Physics
Published
2025-12-27
DOI
https://doi.org/10.1002/mp.70232
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
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Global and local information‐based prostate image registration of prostate‐specific membrane antigen PET/CT and enhanced MRI

D. Xu, Weiwen Zou, Yu'ang Niu, Xiao Deng et al.
Medical Physics
Prostate Cancer Diagnosis and Treatment
article

Global and local information‐based prostate image registration of prostate‐specific membrane antigen PET/CT and enhanced MRI

D. Xu, Weiwen Zou, Yu'ang Niu, Xiao Deng, Huiyu Zhao, Zhiyang Ma
article en

Abstract

This study presents GLNet, a deep learning-based non-rigid registration network that fuses PSMA PET/CT and contrast-enhanced MRI. GLNet outperforms existing methods in registration accuracy and lesion detection, thereby offering a promising approach for integrating structural and functional imaging in clinical PCa diagnosis.

Medical PhysicsVol. 53(1)
Shanghai Jiao Tong University (CN), Ruijin Hospital (CN), Ministry of Education (CL)
Openalex Percentile: Top 28%
Prostate Cancer Diagnosis and Treatment
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