Intestinal barrier healing is superior to transmural healing to prevent disease progression in clinical remittent patients with inflammatory bowel disease

Intestinal barrier healing is superior to transmural healing to prevent disease progression in clinical remittent IBD patients while both barrier and transmural healing showed superiority over endoscopic and histologic remission. Hence, barrier and transmural healing are emerging end-points potentially refining disease monitoring and outcome prediction.

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Publication Details

Journal
Journal of Crohn s and Colitis
Published
2025-12-23
DOI
https://doi.org/10.1093/ecco-jcc/jjaf232
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Intestinal barrier healing is superior to transmural healing to prevent disease progression in clinical remittent patients with inflammatory bowel disease

Till Orlemann, Rolf Janka, Wolfgang Uter, D. Zimmermann et al.
Journal of Crohn s and Colitis
Inflammatory Bowel Disease
article

Intestinal barrier healing is superior to transmural healing to prevent disease progression in clinical remittent patients with inflammatory bowel disease

Till Orlemann, Rolf Janka, Wolfgang Uter, D. Zimmermann, Julia Bodenschatz, Raja Atreya, Timo Räth, Francesco Vitali, Arndt Hartmann, Deike Strobel, M Neurath, Daniele Noviello, Hannah Leonike Hübner
article en

Abstract

Intestinal barrier healing is superior to transmural healing to prevent disease progression in clinical remittent IBD patients while both barrier and transmural healing showed superiority over endoscopic and histologic remission. Hence, barrier and transmural healing are emerging end-points potentially refining disease monitoring and outcome prediction.

Journal of Crohn s and ColitisVol. 20(1)
Friedrich-Alexander-Universität Erlangen-Nürnberg (DE), Universitätsklinikum Erlangen (DE), Comprehensive Cancer Center Erlangen (DE)
Good health and well-being
Openalex Percentile: Top 25%
Inflammatory Bowel Disease
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