Histochemical analysis of mucin expression using mucicarmine and periodic acid-Schiff stains in pleomorphic adenoma and mucoepidermoid carcinoma: An unexplored niche in salivary gland tumour pathology

MEC stained with mucicarmine and PAS showed strong mucin expression in low-grade cases, moderate expression in intermediate-grade cases and weak mucin expression in high-grade cases, showing a statistically significant difference (<i>P</i> < 0.05). PA cases were similarly stained with mucicarmine and PAS, and it was found to have strong mucin expression in the cellular variant, moderate expression in the mixed variant and weak mucin expression was observed in the myxoid variant, giving us a statistically significant result (<i>P</i> < 0.05). Therefore, it was concluded that mucin expression decreased with increasing grades of MEC, but mucin expression increased proportionally with the cellularity of PA.

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Publication Details

Journal
Journal of Oral and Maxillofacial Pathology
Published
2025-10-01
DOI
https://doi.org/10.4103/jomfp.jomfp_184_25
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
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article

Histochemical analysis of mucin expression using mucicarmine and periodic acid-Schiff stains in pleomorphic adenoma and mucoepidermoid carcinoma: An unexplored niche in salivary gland tumour pathology

Sumita Banerjee, Swapan Purkait, Sisca Meida Wati, Abhishek Banerjee et al.
Journal of Oral and Maxillofacial Pathology
Salivary Gland Tumors Diagnosis and Treatment
article

Histochemical analysis of mucin expression using mucicarmine and periodic acid-Schiff stains in pleomorphic adenoma and mucoepidermoid carcinoma: An unexplored niche in salivary gland tumour pathology

Sumita Banerjee, Swapan Purkait, Sisca Meida Wati, Abhishek Banerjee, Sankari P. Kundu, Ananjan Chatterjee
article en

Abstract

MEC stained with mucicarmine and PAS showed strong mucin expression in low-grade cases, moderate expression in intermediate-grade cases and weak mucin expression in high-grade cases, showing a statistically significant difference (<i>P</i> < 0.05). PA cases were similarly stained with mucicarmine and PAS, and it was found to have strong mucin expression in the cellular variant, moderate expression in the mixed variant and weak mucin expression was observed in the myxoid variant, giving us a statistically significant result (<i>P</i> < 0.05). Therefore, it was concluded that mucin expression decreased with increasing grades of MEC, but mucin expression increased proportionally with the cellularity of PA.

Journal of Oral and Maxillofacial PathologyVol. 29(4)
Universitas Airlangga (ID), Regional Institute of Medical Sciences (IN), Gautam Buddha University (IN)
Openalex Percentile: Top 26%
Salivary Gland Tumors Diagnosis and Treatment
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