Mitochondrial transport and axonal mitochondrial density in tauopathy neurons
Our findings demonstrate that decreased kinesin-mediated anterograde transport coupled with sustained retrograde transport might reduce axonal mitochondrial density in tauopathy neurons. This imbalance may contribute to synaptic deficits observed in Alzheimer's disease and other tauopathies.
Authors
- Anusruti Sabui
- Prasad Tammineni
Institutions
- University of Hyderabad (IN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_100949
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00