Metagenomic next-generation sequencing in suspected septic arthritis: A critical appraisal of clinical utility in 82 cases
mNGS provides significant diagnostic value in suspected septic arthritis, particularly in culture-negative cases and those with low SF-WBC counts. It should be used selectively as an adjunct to culture, which remains essential for antimicrobial susceptibility testing.
Authors
- Lihong Yang (ORCID: https://orcid.org/0000-0002-9210-1022)
- Qun Zheng (ORCID: https://orcid.org/0000-0002-2924-9286)
- Lisha Wang (ORCID: https://orcid.org/0000-0002-6482-1073)
- Junyu Jiang
- Jiajia Qin
- Jiajia Wang
- Haijian Ying
- Jiao Qian
Institutions
- Wenzhou Medical University (CN)
- Zhejiang Taizhou Hospital (CN)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1016/j.ijid.2025.108352
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00