Identification and Functional Characterization of the Axolotl ( <i>Ambystoma mexicanum</i> ) Tau Protein
Our microscopy data suggests that tau and β-tubulin III co-localize in axolotl brain tissue. These results will further elucidate our understanding of tau-microtubule interactions in the axolotl, unveil axolotl tau's capacity for aggregation, and position the axolotl as a novel model system in which to investigate how a regenerative organism might respond to an attempt to induce tauopathy.
Authors
- Benoit I. Giasson (ORCID: https://orcid.org/0000-0003-2992-4234)
- Zachary Strickland (ORCID: https://orcid.org/0000-0001-5210-5734)
- Jada Lewis
Institutions
- University of Florida (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_103601
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00