A combined transcriptomic, epigenetic, and functional analysis identifies novel biomarkers in breast cancer
This study identified and experimentally validated four hub genes as potential biomarkers and therapeutic targets in breast cancer. Their expression is regulated by methylation and contributes to tumor progression and immune modulation, highlighting their clinical utility in precision oncology.
Authors
- Adel Abuzenadah (ORCID: https://orcid.org/0000-0003-4969-2071)
- Haneen Alsehli (ORCID: https://orcid.org/0000-0002-6311-5425)
- Yasir Hameed (ORCID: https://orcid.org/0000-0003-2150-4657)
- Majid Alhomrani (ORCID: https://orcid.org/0000-0001-9798-0962)
- H Alkhatabi
- Jaudah Al‐Maghrabi (ORCID: https://orcid.org/0000-0002-0812-9592)
- Bandar K. Baothman (ORCID: https://orcid.org/0000-0003-3866-6935)
- Mamdooh Gari
- Sajjad Karim
- Khalid Mamdooh Gari
- Abdullah G. Bagarish
- Mohammed Natto
Institutions
- Islamia University of Bahawalpur (PK)
- Taif University (SA)
- King Abdulaziz University (SA)
- King Abdulaziz Medical City (SA)
- National Guard Health Affairs (SA)
- University of Sheffield (GB)
Publication Details
- Journal
- Hereditas
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1186/s41065-025-00630-1
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52