Unraveling SLAN+/− monocytes transcriptomics in lupus and extracellular vesicles effects
These findings suggest that EVs transport antigenic molecules and induce transcriptional changes in monocytes toward inflammatory and migratory states, implicating them in LN pathogenesis and highlighting their potential as therapeutic targets.
Authors
- Paula X. Losada (ORCID: https://orcid.org/0000-0002-6651-4720)
- Karen Valdés Álvarez (ORCID: https://orcid.org/0000-0002-1968-4647)
- Juan Antonio Villatoro-García (ORCID: https://orcid.org/0000-0001-5752-7784)
- Mauricio Rojas (ORCID: https://orcid.org/0000-0001-9059-4022)
- Lina María Serrato
- Pedro Carmona-Saez
- Daniel Rodriguez
- Juan Camilo Diaz
- Julio Jaramillo
- Ricardo Pineda
- Gloria M. Vásquez
Institutions
- Universidad de Antioquia (CO)
- Fundación Universitaria Bellas Artes (CO)
- Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research (ES)
Publication Details
- Journal
- Immunobiology
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1016/j.imbio.2025.153153
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00