Postnatal Cytomegalovirus Infection in a Neonatal Intensive Care Unit: A Retrospective Study

pCMV infection in extremely preterm infants is associated with significant morbidity, frequent hematological and respiratory complications, and high mortality. Although antiviral therapy achieved viral clearance in most treated infants, long-term neurodevelopmental impairment was common. Distinguishing sequelae attributable to pCMV from those related to extreme prematurity remains challenging, underscoring the need for prospective studies to better guide management and assess long-term outcomes.

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Publication Details

Journal
Cureus
Published
2025-12-27
DOI
https://doi.org/10.7759/cureus.100175
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
0.00
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article

Postnatal Cytomegalovirus Infection in a Neonatal Intensive Care Unit: A Retrospective Study

Mónica Marçal, Madalena Tuna, Marta Santos Figueiredo, Denise Baganho et al.
Cureus
Cytomegalovirus and herpesvirus research
article

Postnatal Cytomegalovirus Infection in a Neonatal Intensive Care Unit: A Retrospective Study

Mónica Marçal, Madalena Tuna, Marta Santos Figueiredo, Denise Baganho, Inês F Fernandes
article en

Abstract

pCMV infection in extremely preterm infants is associated with significant morbidity, frequent hematological and respiratory complications, and high mortality. Although antiviral therapy achieved viral clearance in most treated infants, long-term neurodevelopmental impairment was common. Distinguishing sequelae attributable to pCMV from those related to extreme prematurity remains challenging, underscoring the need for prospective studies to better guide management and assess long-term outcomes.

CureusVol. 17(12)
Unidade Local de Saúde de São José (PT), Administração Regional de Saúde de Lisboa e Vale do Tejo (PT), Centro Hospitalar de Lisboa Ocidental (PT), Hospital de São Bernardo (PT), Universidade Nova de Lisboa (PT)
Good health and well-being
Openalex Percentile: Top 30%
Cytomegalovirus and herpesvirus research
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