Sex differences among patients with giant cell arteritis: insights from the Spanish ARTESER Registry
Women more frequently exhibited the extracranial phenotype, required more csDMARDs, and experienced a higher incidence of fractures. In contrast, men more commonly presented with the mixed phenotype, had more cataracts, and showed a higher mortality rate. These findings highlight the importance of integrating sex as a key biological variable in GCA research and clinical management to support more tailored and effective therapeutic strategies.
Authors
- Marta Domínguez-Álvaro (ORCID: https://orcid.org/0000-0002-4057-5971)
- F. Sánchez-Alonso
- Ana Paula Cacheda
- E. De Miguel
- J Urgellés
- Elisa Fernández-Fernández (ORCID: https://orcid.org/0000-0002-1628-5042)
- C. Larena Grijalba
- Ismael González Fernández
- Cristina Valero Martínez
- J. Mendizabal
- Íñigo Hernández-Rodríguez
- N. Garrido-Puñal
- Nair Torrado Pérez
- E Cortina
- V. Angeles
- José L. Hernández (ORCID: https://orcid.org/0000-0002-6585-8847)
- María Jesús García-Villanueva (ORCID: https://orcid.org/0000-0002-0441-6623)
- J Narvaez
- Maite Silva-Díaz
- Joaquín Belzunegui
- I. Calvo (ORCID: https://orcid.org/0000-0001-8008-204X)
- Vicente Aldasoro
- Julio Sánchez Martín (ORCID: https://orcid.org/0000-0002-7623-057X)
- Amalia Sanchez-Andrade Fernández
- Clara Moriano
- Noelia Alvarez Rivas
- J. Loricera (ORCID: https://orcid.org/0000-0003-4754-0277)
- J. L. Filloy
- Lucia Silva Fernández
- Clara Aguilera Cros
- Alberto Ruiz Román
- Paula Estrada Alarcón (ORCID: https://orcid.org/0000-0002-9827-5680)
- T. Pérez Sandoval
- M. Alcalde Villar (ORCID: https://orcid.org/0009-0003-7629-085X)
- Clara Molina Almela (ORCID: https://orcid.org/0000-0003-2556-2512)
- D. Fernandez-Lozano (ORCID: https://orcid.org/0000-0001-9650-1296)
- Leticia Leon Mateos
- Ana Milena Millán
- Javier Calvo Catalá
- Félix Cabero del Pozo
- Alejandro Muñoz Jimenez
- Anderson Huaylla
- Ana Belén Rodríguez Cambrón
- Santos Castañeda
- E. Díez Álvarez
- Ana F Cruz Valenciano
- Ricardo Blanco
- Lydia Abasolo
- Patricia Moya-Alvarado
- ARTESER Project Collaborative Group
- María Sagrario Bustabad Reyes
- Rafael Benito Melero
- Selene Labrada Arrabal
- Loreto Horcada Rubio
- Jaime Calvo Allen
- Tomás Almorza
- Tarek Carlos Salman Monte
- Aliuska Palomeque Vargas
- Marta Serrano Warleta
- Tomás Ramón Vázquez Rodríguez
- Ceferino Barbazán
- Jose A Román Ivorra
- Berta Magallares
- Carlota Laura Iñiguez Ubiaga
- Vette Casafont
- John Guzman
- Cesar Antonio Egues Dubuc
- Amalia Rueda Cid
- María García González
- Inmaculada Paniagua Zudaire
- Miren Uriarte-Ecenarro
- Cristina Macia Villa
- Ricardo Gutiérrez Polo
- Joan Calvet Fontova
- Carlos García Porrúa
- Patricia Carreira
- Pia Mercedes Lois Bermejo
- Laura Garrido Courel
- Vanesa Hernández Hernández
- Judit Lluch
- Francisco Ortiz Sanjuán
- Eva Álvarez de Andrés
- Inmaculada Ros Vilamajó
- Jordi Camins
- Luis López Domínguez
- Cristina Campos Fernández
- María Concepción Fito Manteca
- Antonio Juan Mas
- Elide Toniolo
- Carlos Galisteo Lencastre Da Veiga
- Marina Tortosa Cabañas
Institutions
- Universidad de Cantabria (ES)
- Hospital Universitario La Paz (ES)
- Hospital de Sant Pau (ES)
- Bellvitge University Hospital (ES)
- University Hospital Complex Of Vigo (ES)
- Hospital Clínico San Carlos (ES)
- Hospital Universitari i Politècnic La Fe (ES)
- Complejo Hospitalario de Navarra (ES)
- Marqués de Valdecilla University Hospital (ES)
- Sociedad Española de Reumatología (ES)
- Instituto de Investigación Marqués de Valdecilla (ES)
- Hospital de Galdakao (ES)
- Hospital Universitario de La Princesa (ES)
- Hospital de Sant Joan Despí Moisès Broggi (ES)
- Donostiako Unibertsitate Ospitalea (ES)
- Complexo Hospitalario Universitario A Coruña (ES)
- Hospital Universitario Virgen del Rocío (ES)
- Hospital Universitario de León (ES)
- Hospital Universitario Ramón y Cajal (ES)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1093/rheumatology/keaf689
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00