A fetal autopsy study on congenital malformations among stillbirths in a tertiary care hospital

The present study was conducted to determine the pattern of distribution of congenital anomalies based on the system of involvement through fetal autopsy. A descriptive, cross-sectional study was performed on 50 stillborn fetuses. The objective of this study is to find out the association between congenital anomalies and maternal factors, congenital anomalies and fetal factors, and the association between autopsy findings and antenatal ultrasound reports. Each stillborn fetus was classified based on birth weight, gestational age, maternal age, gravidity of the mother, and socioeconomic status of the parents. The central nervous system anomalies (36%) are the most commonly observed congenital anomalies. The chi-square test showed a significant association between maternal medical disorders and congenital anomalies (p < 0.05). The chi-square test showed a significant association between maternal medical disorders and congenital anomalies (p < 0.05). The autopsy confirmed the antenatal ultrasound findings in 40 (80%) of the cases. There were significant additional findings observed in 7 (14%) cases, and ultrasound diagnosis was completely changed in 3 (6%) cases, after the final autopsy procedure. It should be mandatory to have an autopsy study for all the stillborn fetuses to predict and counsel for safe future pregnancy outcomes.

Authors

Institutions

Publication Details

Journal
Scientific Reports
Published
2025-12-27
DOI
https://doi.org/10.1038/s41598-025-33022-6
Primary Topic
Autopsy Techniques and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A fetal autopsy study on congenital malformations among stillbirths in a tertiary care hospital

P Vinutha, Manjunath G.V, Sapna Patel M. C, Narayanappa D et al.
Scientific Reports
Autopsy Techniques and Outcomes
article

A fetal autopsy study on congenital malformations among stillbirths in a tertiary care hospital

P Vinutha, Manjunath G.V, Sapna Patel M. C, Narayanappa D, Sinchana N, Shrisagar R. A
article en

Abstract

The present study was conducted to determine the pattern of distribution of congenital anomalies based on the system of involvement through fetal autopsy. A descriptive, cross-sectional study was performed on 50 stillborn fetuses. The objective of this study is to find out the association between congenital anomalies and maternal factors, congenital anomalies and fetal factors, and the association between autopsy findings and antenatal ultrasound reports. Each stillborn fetus was classified based on birth weight, gestational age, maternal age, gravidity of the mother, and socioeconomic status of the parents. The central nervous system anomalies (36%) are the most commonly observed congenital anomalies. The chi-square test showed a significant association between maternal medical disorders and congenital anomalies (p < 0.05). The chi-square test showed a significant association between maternal medical disorders and congenital anomalies (p < 0.05). The autopsy confirmed the antenatal ultrasound findings in 40 (80%) of the cases. There were significant additional findings observed in 7 (14%) cases, and ultrasound diagnosis was completely changed in 3 (6%) cases, after the final autopsy procedure. It should be mandatory to have an autopsy study for all the stillborn fetuses to predict and counsel for safe future pregnancy outcomes.

Scientific ReportsVol. 16(1)
JSS Academy of Higher Education and Research (IN)
Good health and well-being
Openalex Percentile: Top 31%
Autopsy Techniques and Outcomes
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

A fetal autopsy study on congenital malformations among stillbirths in a tertiary care hospital — P Vinutha, Manjunath G.V, et al. · Scientific Reports (2025) | TGRS Research Map | TGRS