Infantile Acute Colonic Pseudo-Obstruction (Ogilvie's Syndrome) Following Use of Dicyclomine in Infantile Colic- A Case Report

Abstract Infantile colic is a common functional gastrointestinal disorder characterized by excessive crying in otherwise healthy infants, Infantile colic is a common, self-limiting condition. Pharmacological interventions, particularly anticholinergic agents, have historically been attempted and used but are associated with significant risks and not recommended due to safety concerns. We report a 6-week old female infant who developed acute colonic pseudo-obstruction following administration of anticolic medication, dicyclomine, an atropine derivative prescribed for colic relief. Patient was successfully treated conservatively for a prolonged period and who subsequently developed congenital colorectal motility disorder on longer term follow up. This case underscores the dangers of anticholinergic therapy in infants and highlights the importance of non-pharmacological management strategies.