Costs associated with increasing numbers of Medicare beneficiaries with HIV aged 65 years and older from 2026 to 2035

<b>Question:</b> As the population of people with HIV in the US grows older, what are the expected costs to Medicare and the impact of antiretroviral therapy (ART) costs?<b>Findings:</b> Using microsimulation modeling, we find that the number of Medicare beneficiaries with HIV 65y+ on ART will more than double over the next decade. At current costs of ART and health care-associated inflation, total 10-year costs to Medicare are anticipated to be $196.5 billion; reducing ART costs through the Inflation Reduction Act or generic ART could lower Medicare spending by 40%.<b>Meaning:</b> Efforts to reduce ART costs, while maintaining access to high-quality ART, are critical to reduce total Medicare costs as more people with HIV are anticipated to enroll in Medicare in the next 10 years.

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Publication Details

Journal
medRxiv
Published
2025-12-27
DOI
https://doi.org/10.64898/2025.12.19.25342703
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Costs associated with increasing numbers of Medicare beneficiaries with HIV aged 65 years and older from 2026 to 2035

Lucas Gerace, Jessica Phelan, Endel John Orav, Keri N. Althoff et al.
medRxiv
HIV-related health complications and treatments
article

Costs associated with increasing numbers of Medicare beneficiaries with HIV aged 65 years and older from 2026 to 2035

Lucas Gerace, Jessica Phelan, Endel John Orav, Keri N. Althoff, P E Sax, Anne M. Neilan, Dannie Dai, John Giardina, Luke Ang, Parastu Kasaie, Ciara Duggan, Satoshi Koiso, Ankur Pandya, Florence Ebem, Grace Luu, Emily P Hyle, Elizabeth Humes, Kenneth A Freedberg, Jose Francisco Figueroa
article en

Abstract

<b>Question:</b> As the population of people with HIV in the US grows older, what are the expected costs to Medicare and the impact of antiretroviral therapy (ART) costs?<b>Findings:</b> Using microsimulation modeling, we find that the number of Medicare beneficiaries with HIV 65y+ on ART will more than double over the next decade. At current costs of ART and health care-associated inflation, total 10-year costs to Medicare are anticipated to be $196.5 billion; reducing ART costs through the Inflation Reduction Act or generic ART could lower Medicare spending by 40%.<b>Meaning:</b> Efforts to reduce ART costs, while maintaining access to high-quality ART, are critical to reduce total Medicare costs as more people with HIV are anticipated to enroll in Medicare in the next 10 years.

medRxiv
Brigham and Women's Hospital (US), Harvard University (US), Johns Hopkins University (US), Massachusetts General Hospital (US)
Massachusetts General Hospital, National Institutes of Health
Openalex Percentile: Top 25%
HIV-related health complications and treatments
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Costs associated with increasing numbers of Medicare beneficiaries with HIV aged 65 years and older from 2026 to 2035 — Lucas Gerace, Jessica Phelan, et al. · medRxiv (2025) | TGRS Research Map | TGRS