Prolonged Versus Intermittent Beta‐Lactam Antibiotic Infusions in Paediatric Critical Care: A Systematic Review and Meta‐Analysis
Available studies on prolonged infusions of beta lactams in PICU patients are limited and of low quality. Further research is needed to assess for clinical benefits associated with prolonged beta-lactam infusions for treatment of severe infection.
Authors
- Kerina J. Denny (ORCID: https://orcid.org/0000-0001-9901-5736)
- Kinga Anna Budai
- Patricia Gilholm (ORCID: https://orcid.org/0000-0001-8135-1520)
- KRISTEN S. GIBBONS (ORCID: https://orcid.org/0000-0002-5679-0932)
- Sainath Raman (ORCID: https://orcid.org/0000-0002-0152-9980)
- C. A. Lodi (ORCID: https://orcid.org/0000-0003-3525-6922)
- James McCullough
- Gwendoline Ragonnet (ORCID: https://orcid.org/0000-0001-9044-7380)
- Renate Le Marsney (ORCID: https://orcid.org/0000-0001-9271-8594)
- Jay Roberts (ORCID: https://orcid.org/0009-0005-0620-8835)
- Mahmoud Obeidat
- Kirsty O‘Keefe
- Agathe Béranger
- Noppadol Wacharachaisurapol
Institutions
- Semmelweis University (HU)
- Griffith University (AU)
- Hôpital Necker-Enfants Malades (FR)
- Queensland Health (AU)
- Children's Medical Research Institute (AU)
- Chulalongkorn University (TH)
- The University of Queensland (AU)
- Université de Montpellier (FR)
- Université Paris Cité (FR)
- Royal Brisbane and Women's Hospital (AU)
- Gold Coast Hospital (AU)
- Metro South Health (AU)
- Children’s Health Queensland Hospital and Health Service (AU)
- Sorbonne Paris Cité (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital de la Timone (FR)
- Children's Health Queensland Hospital and Health Service (AU)
- Université de Nîmes (FR)
Publication Details
- Journal
- Journal of Paediatrics and Child Health
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1111/jpc.70275
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00