The mechanistic role of non-coding RNAs in febrile seizures in children: their potential as biomarkers and therapeutic targets—a systematic review

NcRNAs serve as dynamic regulators in the pathogenesis of FSs, providing valuable insights for diagnosis and treatment. They hold remarkable potential as non-invasive biomarkers and therapeutic targets. However, future research should prioritize validating the findings in clinical cohorts, elucidating causal mechanisms, and addressing translational challenges, such as standardization and delivery systems, to advance personalized medicine for pediatric FSs.

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Publication Details

Journal
Translational Pediatrics
Published
2025-12-01
DOI
https://doi.org/10.21037/tp-2025-15
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

The mechanistic role of non-coding RNAs in febrile seizures in children: their potential as biomarkers and therapeutic targets—a systematic review

Wan-Xing Ou, Wei-Ying Wang, Li-Qin Lian, Ru-Juan Ling et al.
Translational Pediatrics
Epilepsy research and treatment
article

The mechanistic role of non-coding RNAs in febrile seizures in children: their potential as biomarkers and therapeutic targets—a systematic review

Wan-Xing Ou, Wei-Ying Wang, Li-Qin Lian, Ru-Juan Ling, Shu-Hua Li, Shu-Yin Wang
article en

Abstract

NcRNAs serve as dynamic regulators in the pathogenesis of FSs, providing valuable insights for diagnosis and treatment. They hold remarkable potential as non-invasive biomarkers and therapeutic targets. However, future research should prioritize validating the findings in clinical cohorts, elucidating causal mechanisms, and addressing translational challenges, such as standardization and delivery systems, to advance personalized medicine for pediatric FSs.

Translational PediatricsVol. 14(12)
Guangzhou Medical University (CN)
Openalex Percentile: Top 32%
Epilepsy research and treatment
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