The mechanistic role of non-coding RNAs in febrile seizures in children: their potential as biomarkers and therapeutic targets—a systematic review
NcRNAs serve as dynamic regulators in the pathogenesis of FSs, providing valuable insights for diagnosis and treatment. They hold remarkable potential as non-invasive biomarkers and therapeutic targets. However, future research should prioritize validating the findings in clinical cohorts, elucidating causal mechanisms, and addressing translational challenges, such as standardization and delivery systems, to advance personalized medicine for pediatric FSs.
Authors
- Wan-Xing Ou
- Wei-Ying Wang
- Li-Qin Lian
- Ru-Juan Ling
- Shu-Hua Li
- Shu-Yin Wang
Institutions
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Translational Pediatrics
- Published
- 2025-12-01
- DOI
- https://doi.org/10.21037/tp-2025-15
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00