Feasibility Study of Soybean Oil-Fortified Foods to Alter Blood Content of Linoleic Acid and Body Weight: A Randomized Double-Masked Placebo-Controlled Crossover Trial

Foods can be used to deliver 30 g/d of dietary oil for 4 wk to impact linoleic acid biomarkers without incurring body weight changes. These foods are useful for future randomized controlled double-masked clinical trials assessing the impact of dietary oils on energy metabolism. The study was registered at clinicaltrials.gov as NCT04975763 (https://clinicaltrials.gov/study/NCT04975763).

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Publication Details

Journal
Journal of Nutrition
Published
2025-12-27
DOI
https://doi.org/10.1016/j.tjnut.2025.101288
Primary Topic
Fatty Acid Research and Health
Type
article
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article

Feasibility Study of Soybean Oil-Fortified Foods to Alter Blood Content of Linoleic Acid and Body Weight: A Randomized Double-Masked Placebo-Controlled Crossover Trial

Rachel M. Cole, Martha A. Belury, Eric Colombo, Austin Angelotti et al.
Journal of Nutrition
Fatty Acid Research and Health
article

Feasibility Study of Soybean Oil-Fortified Foods to Alter Blood Content of Linoleic Acid and Body Weight: A Randomized Double-Masked Placebo-Controlled Crossover Trial

Rachel M. Cole, Martha A. Belury, Eric Colombo, Austin Angelotti, Genevieve C. Sparagna, Rolando E Choriego, Rafael Jimenez-Flores, Andy Ni
article en

Abstract

Foods can be used to deliver 30 g/d of dietary oil for 4 wk to impact linoleic acid biomarkers without incurring body weight changes. These foods are useful for future randomized controlled double-masked clinical trials assessing the impact of dietary oils on energy metabolism. The study was registered at clinicaltrials.gov as NCT04975763 (https://clinicaltrials.gov/study/NCT04975763).

Journal of NutritionVol. 156(2)
The Ohio State University Wexner Medical Center (US), University of Colorado Anschutz Medical Campus (US), The Ohio State University (US), Penn State Milton S. Hershey Medical Center (US)
Openalex Percentile: Top 35%
Fatty Acid Research and Health
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Feasibility Study of Soybean Oil-Fortified Foods to Alter Blood Content of Linoleic Acid and Body Weight: A Randomized Double-Masked Placebo-Controlled Crossover Trial — Rachel M. Cole, Martha A. Belury, et al. · Journal of Nutrition (2025) | TGRS Research Map | TGRS