Guided de-escalation of antiplatelet treatment in patients at high atherothrombotic risk presenting with acute coronary syndrome: a <i>post hoc</i> analysis of the TROPICAL-ACS trial
Early PFT-guided de-escalation from prasugrel to clopidogrel was safe across atherothrombotic risk categories, supporting individualized DAPT optimization in ACS patients with both low and high ischemic risk.
Authors
- T. Geisler
- L. KOLTOWSKI
- Lisa Groß
- Konstantinos D. Rizas (ORCID: https://orcid.org/0000-0002-5993-0339)
- Dominik Naumann (ORCID: https://orcid.org/0009-0005-3911-6144)
- Ralph Hein
- Dietmar Trenk (ORCID: https://orcid.org/0000-0003-0505-7121)
- Monika Baylacher
- Birgit Vogel
- Kurt Huber (ORCID: https://orcid.org/0000-0003-1695-3378)
- Steffen Massberg
- A. G. Low
- Martin Orban
- Mathias Orban
- Dirk Sibbing
- Serdar Farhan
- Zenon Huczek
Institutions
- Cardiovascular Institute of the South (US)
- Medical University of Warsaw (PL)
- Lenox Hill Hospital (US)
- LMU Klinikum (DE)
- University of Applied Sciences Burgenland (AT)
- Ludwig Boltzmann Institute for Age Research (AT)
- University Children's Hospital Tübingen (DE)
- German Centre for Cardiovascular Research (DE)
- Universitäts-Herzzentrum Freiburg-Bad Krozingen (DE)
- Sexual Health Clinic (FI)
- University of Tübingen (DE)
- Ludwig-Maximilians-Universität München (DE)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- European Heart Journal Acute Cardiovascular Care
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1093/ehjacc/zuaf172
- Primary Topic
- Antiplatelet Therapy and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00