Histone acetyltransferase KAT6A contributes to colon cancer malignant progression by inhibiting ferroptosis
KAT6A promotes the proliferation of CC cells and suppresses ferroptosis via epigenetic regulation of GPX4. Our work presented KAT6A as a potential diagnostic and therapeutic target for treatment CC.
Authors
- Dong Sun (ORCID: https://orcid.org/0009-0000-8725-4334)
- Xiaoqiao Zhang
- Yugang Jiang
- Hongyuan Chen
- Junyu Huo
- Hongguang Sheng
Institutions
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1186/s12885-025-15368-2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00