Efficacy and Safety of Abrocitinib and Dupilumab in the Treatment of Moderate-to-Severe Atopic Dermatitis

Both abrocitinib and dupilumab can significantly relieve pruritus and improve quality of life in patients with moderate-to-severe AD at 24 weeks after treatment, but abrocitinib is more effective in relieving pruritus. Both abrocitinib and dupilumab have high safety, but require attention for gastrointestinal symptoms and conjunctivitis, respectively.

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Publication Details

Journal
Journal of Cutaneous Medicine and Surgery
Published
2025-12-26
DOI
https://doi.org/10.1177/12034754251404468
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and Safety of Abrocitinib and Dupilumab in the Treatment of Moderate-to-Severe Atopic Dermatitis

Xinlin Huang, X Wang, Sheng Wang, Mi Zhang
Journal of Cutaneous Medicine and Surgery
Dermatology and Skin Diseases
article

Efficacy and Safety of Abrocitinib and Dupilumab in the Treatment of Moderate-to-Severe Atopic Dermatitis

Xinlin Huang, X Wang, Sheng Wang, Mi Zhang
article en

Abstract

Both abrocitinib and dupilumab can significantly relieve pruritus and improve quality of life in patients with moderate-to-severe AD at 24 weeks after treatment, but abrocitinib is more effective in relieving pruritus. Both abrocitinib and dupilumab have high safety, but require attention for gastrointestinal symptoms and conjunctivitis, respectively.

Journal of Cutaneous Medicine and Surgery
Hubei University of Medicine (CN), First Affiliated Hospital of Shihezi University Medical College (CN)
Openalex Percentile: Top 24%
Dermatology and Skin Diseases
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