Safety and efficacy of allogeneic umbilical cord blood cells and erythropoietin combination therapy in patients with subacute stroke
In conclusion, rhEPO can enhance the efficacy of UCB cells in patients with subacute stroke, without causing harmful effects. This exploratory finding may provide evidence for the potential use of UCB + EPO combination therapy for neurological recovery following stroke. Trial registration URL: https://clinicaltrials.gov/ct2/show/NCT04013646 .
Authors
- Jee In Choi
- Sean S. S. Hwang (ORCID: https://orcid.org/0000-0002-1922-7964)
- Mi Ri Suh (ORCID: https://orcid.org/0000-0003-1759-9198)
- Hyun Im Moon (ORCID: https://orcid.org/0000-0003-3430-1824)
- S.H. Cho (ORCID: https://orcid.org/0000-0003-0082-9890)
- J. E. Lee
- Doyoung Lee
- Minyoung Kim
- Jong Moon Kim
- Seyoung Shin
- Yun-Hee Kim
- Hyeok Gyu Kwon
Institutions
- Eulji University (KR)
- Konkuk University (KR)
- Bundang Jesaeng Hospital (KR)
- Konkuk University Medical Center (KR)
- Regenerative Medicine Institute (MX)
- CHA University Bundang Medical Center (KR)
- CHA University (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1186/s13287-025-04856-8
- Primary Topic
- Erythropoietin and Anemia Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00