Interaction of serum zinc and copper status with fatty acid desaturases on incidence of type 2 diabetes in the EPIC-Potsdam study
Zn and Cu status modified the relationship between FA desaturases and T2D risk. This was supported by serum Zn and Cu levels and by genetic variation related to their transport and homeostasis.
Authors
- Olga Kuxhaus
- Susanne Jäger
- Tanja Schwerdtle (ORCID: https://orcid.org/0000-0002-4873-7488)
- Hajo Haase (ORCID: https://orcid.org/0000-0002-1622-8718)
- Matthias Bernd Schulze (ORCID: https://orcid.org/0000-0002-0830-5277)
- Anna P. Kipp (ORCID: https://orcid.org/0000-0002-3307-1038)
- Fabian Eichelmann (ORCID: https://orcid.org/0000-0002-3975-5596)
- Olha Bezuhla
- Marcela Prada
Institutions
- Max Rubner Institut (DE)
- Deutsches Diabetes-Zentrum e.V. (DE)
- German Institute of Human Nutrition (DE)
- Heinrich Heine University Düsseldorf (DE)
- Technische Universität Berlin (DE)
- Friedrich Schiller University Jena (DE)
Publication Details
- Journal
- Redox Biology
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1016/j.redox.2025.103998
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00