<scp>SGLT</scp> ‐2 Inhibitors Are Associated With Lower Mortality and Decompensation in Patients With <scp>MASH</scp> Cirrhosis and Type 2 Diabetes

SGLT-2 inhibitors are associated with a reduced risk of all-cause mortality in patients with MASH cirrhosis and T2DM, which may be partly attributable to a lower risk of hepatic decompensation and subsequent events. Further studies are warranted as SGLT-2 inhibitors may serve as an adjunctive therapy for patients with MASH cirrhosis.

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Publication Details

Journal
Liver International
Published
2025-12-27
DOI
https://doi.org/10.1111/liv.70490
Citations
1
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.35
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article

SGLT ‐2 Inhibitors Are Associated With Lower Mortality and Decompensation in Patients With MASH Cirrhosis and Type 2 Diabetes

Raffi Karagozian, J.A. Porres, Meena B. Bansal, Carlos Alatorre et al.
1 citations
Liver International
Liver Disease Diagnosis and Treatment
1.35
article

SGLT ‐2 Inhibitors Are Associated With Lower Mortality and Decompensation in Patients With MASH Cirrhosis and Type 2 Diabetes

Raffi Karagozian, J.A. Porres, Meena B. Bansal, Carlos Alatorre, Paul T. Kröner, Donghyun Ko, Do Han Kim, F Lukens, Luis M. Nieto, Vincent L. Chen, Donghee Kim, Pedro Palacios Argueta, Karn Wijarnpreecha
article en
1 citations

Abstract

SGLT-2 inhibitors are associated with a reduced risk of all-cause mortality in patients with MASH cirrhosis and T2DM, which may be partly attributable to a lower risk of hepatic decompensation and subsequent events. Further studies are warranted as SGLT-2 inhibitors may serve as an adjunctive therapy for patients with MASH cirrhosis.

Liver InternationalVol. 46(2)
Tufts University (US), New York City Health and Hospitals Corporation (US), University of Arizona (US), Emory University (US), University of Phoenix (US), University of Michigan (US), Metropolitan Hospital Center (US), Jacksonville College (US), Bridgeport Hospital (US), Banner - University Medical Center Phoenix (US), Mayo Clinic Health System (US), Riverside Regional Medical Center (US), Universidad Francisco Marroquín (GT), Stanford University (US), Icahn School of Medicine at Mount Sinai (US)
Good health and well-being
Openalex Percentile: Top 13%
Liver Disease Diagnosis and Treatment
1.35
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