Micro-elimination of Hepatitis C virus (HCV) infection in the General Population Cohort in rural Uganda: Long-term follow-up to assess feasibility and outcomes of a screening and treatment intervention
Among individuals offered DAA treatment, acceptance and cure rate were high. In this setting, HCV infection likely contributed to mortality, and affected older adults and migrants, suggesting these groups might be priorities for future micro-elimination programmes.
Authors
- Ronald Makanga (ORCID: https://orcid.org/0009-0001-8430-8234)
- Chris Davis
- Moffat Nyirenda
- Geraldine O’Hara (ORCID: https://orcid.org/0000-0002-1922-9492)
- Clara Wekesa (ORCID: https://orcid.org/0000-0001-6064-237X)
- Sheila Lumley (ORCID: https://orcid.org/0000-0001-6825-9324)
- Robert Newton (ORCID: https://orcid.org/0000-0001-6715-9153)
- Richard Ndungutse
- Elizabeth Waddilove (ORCID: https://orcid.org/0000-0003-3228-3845)
- George S. Mgomella (ORCID: https://orcid.org/0000-0002-9525-7612)
- Janet Seeley (ORCID: https://orcid.org/0000-0002-0583-5272)
- Beatrice Kimono
- Philippa C Matthews
- Emma Thomson
- Ponsiano Ocama
- Joseph Mugisha
Institutions
- University of London (GB)
- The Francis Crick Institute (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Medawar Building for Pathogen Research (GB)
- African Population and Health Research Center (KE)
- MRC University of Glasgow Centre for Virus Research (GB)
- Oxford University Hospitals NHS Trust (GB)
- University College London (GB)
- Makerere University (UG)
- Uganda Virus Research Institute (UG)
Publication Details
- Journal
- Journal of Clinical Virology
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1016/j.jcv.2025.105911
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00