A case series of Budd-Chiari syndrome in pregnancy undergoing elective caesarean section: Anaesthetic considerations

Budd–Chiari syndrome (BCS) is an uncommon disorder caused by hepatic venous outflow obstruction leading to hepatomegaly, ascites, and abdominal pain. The condition poses significant challenges during pregnancy due to altered hepatic function, hypercoagulability, and increased haemodynamic demands. We present a series of three pregnant patients with known BCS scheduled for elective lower segment caesarean section, each managed using a multidisciplinary approach. All patients were on anticoagulation therapy during pregnancy and underwent careful preoperative assessment with haematology, gastroenterology, and obstetric consultations. Anticoagulants were discontinued 24 hours before surgery. Two patients received spinal anaesthesia, while one underwent general anaesthesia due to coagulopathy (international normalised ratio 1.6). Estimated intraoperative blood loss ranged from 800 to 1000 ml. All patients remained haemodynamically stable throughout the procedure and the postoperative period. Anticoagulation was resumed within 12–24 hours postoperatively, and no maternal or neonatal complications were reported. Pregnancy complicated by BCS requires vigilant planning and individualised anaesthetic management. A multidisciplinary approach, appropriate timing of anticoagulation discontinuation, and careful intraoperative monitoring are crucial to optimise maternal and foetal outcomes. Elective caesarean delivery in a tertiary care setting with close coordination between obstetrician, anaesthesiologist, haematology, and hepatology teams can significantly improve prognosis in women with BCS.

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Published
2025-12-27
DOI
https://doi.org/10.25259/peak_11_2025
Primary Topic
Liver Disease and Transplantation
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article
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article

A case series of Budd-Chiari syndrome in pregnancy undergoing elective caesarean section: Anaesthetic considerations

Yogita Patil, Mahalakshmi Ethiraj
Liver Disease and Transplantation
article

A case series of Budd-Chiari syndrome in pregnancy undergoing elective caesarean section: Anaesthetic considerations

Yogita Patil, Mahalakshmi Ethiraj
article en

Abstract

Budd–Chiari syndrome (BCS) is an uncommon disorder caused by hepatic venous outflow obstruction leading to hepatomegaly, ascites, and abdominal pain. The condition poses significant challenges during pregnancy due to altered hepatic function, hypercoagulability, and increased haemodynamic demands. We present a series of three pregnant patients with known BCS scheduled for elective lower segment caesarean section, each managed using a multidisciplinary approach. All patients were on anticoagulation therapy during pregnancy and underwent careful preoperative assessment with haematology, gastroenterology, and obstetric consultations. Anticoagulants were discontinued 24 hours before surgery. Two patients received spinal anaesthesia, while one underwent general anaesthesia due to coagulopathy (international normalised ratio 1.6). Estimated intraoperative blood loss ranged from 800 to 1000 ml. All patients remained haemodynamically stable throughout the procedure and the postoperative period. Anticoagulation was resumed within 12–24 hours postoperatively, and no maternal or neonatal complications were reported. Pregnancy complicated by BCS requires vigilant planning and individualised anaesthetic management. A multidisciplinary approach, appropriate timing of anticoagulation discontinuation, and careful intraoperative monitoring are crucial to optimise maternal and foetal outcomes. Elective caesarean delivery in a tertiary care setting with close coordination between obstetrician, anaesthesiologist, haematology, and hepatology teams can significantly improve prognosis in women with BCS.

Vol. 1
King Edward Memorial Hospital and Seth G.S. Medical College (IN)
Good health and well-being
Openalex Percentile: Top 30%
Liver Disease and Transplantation
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A case series of Budd-Chiari syndrome in pregnancy undergoing elective caesarean section: Anaesthetic considerations — Yogita Patil, Mahalakshmi Ethiraj · (2025) | TGRS Research Map | TGRS