Pituitary Entry Zone: Newly Midline Hypovascular Area in Pituitary Gland
This study identifies a distinct zone of relative hypovascularity along the sagittal midline of the human pituitary gland, which we propose naming the pituitary entry zone. This anatomical finding offers a potential histologic basis for the observed preservation of pituitary function after midline surgical approaches. While limited by a small sample size, these results highlight a previously under-characterized aspect of pituitary angioarchitecture that may represent a safer corridor for surgical intervention. Further investigation correlating this anatomical finding with postoperative outcomes is warranted.
Authors
- Carlos Castillo-Rangel (ORCID: https://orcid.org/0000-0003-2956-5112)
- Matías Baldoncini (ORCID: https://orcid.org/0000-0001-9323-8306)
- Cristofer Zarate-Calderon (ORCID: https://orcid.org/0000-0002-6039-3745)
- Edgar G Ordonez-Rubiano
- Gerardo Marín (ORCID: https://orcid.org/0000-0002-9370-4837)
- Carolina Galicia-Ramirez
- Gustavo Leonel-Garavaglia
- Juan Villalonga
- Karla Akezalli Hernández-Contreras
- Álvaro Campero
- Daniel Casanova
Institutions
- National University of Tucumán (AR)
- Universidad Veracruzana (MX)
- Universidad de Buenos Aires (AR)
- Fundación Santa Fe de Bogotá (CO)
- Fundación Universitaria de Ciencias de la Salud (CO)
- Universidad de Aconcagua (CL)
- University of Valparaíso (CL)
- Institute for Social Security and Services for State Workers (MX)
Publication Details
- Journal
- World Neurosurgery
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1016/j.wneu.2025.124768
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00