Multigenerational effects of uranium exposure reveal stronger testicular dysregulation in the second generation
Uranium may impair testicular function, with more pronounced effects observed in the F2 generation. These findings highlight its potential for multigenerational toxicity and underscore the need for further research into its impact on human reproductive health.
Authors
- Audrey Legendre (ORCID: https://orcid.org/0000-0001-6219-0100)
- Céline Gloaguen
- Catherine Defoort
- Pascal Froment (ORCID: https://orcid.org/0000-0002-7388-9598)
- M. Souidi
- Stéphane Grison (ORCID: https://orcid.org/0000-0002-1569-7547)
- Mohamed Amine Benadjaoud (ORCID: https://orcid.org/0000-0002-9895-6654)
- Dimitri Kereselidze
- Christelle Elie
- Nawel Saci
- Philippe Lestaevel
- Sophia Murat El Houdigui
Institutions
- Institut de Radioprotection et de Sûreté Nucléaire (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Aix-Marseille Université (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Physiologie de la Reproduction et des Comportements (FR)
- Nutrition, Obésité et Risque Thrombotique (FR)
- Autorité de sûreté nucléaire et de radioprotection (FR)
Publication Details
- Journal
- Current Research in Toxicology
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1016/j.crtox.2025.100279
- Primary Topic
- Radioactivity and Radon Measurements
- Type
- article
- Field-Weighted Citation Impact
- 0.00