Tumor Necrosis Factor–Induced Neuropilin‐2 in Fibroblast‐Like Synoviocytes Exacerbates Rheumatoid Arthritis
TNF-induced NRP2 drives inflammatory persistence in RA and serves as a promising diagnostic biomarker. Targeting the TNF-p65-NRP2 axis in FLS may offer a novel strategy for mitigating arthritis progression.
Authors
- Haitao Niu
- Yuxin Deng
- Kun Jin (ORCID: https://orcid.org/0000-0002-8208-7052)
- Jingjing Ran
- Ying Yang (ORCID: https://orcid.org/0000-0002-1822-9546)
- Zhiyong Miao
- Tong Li (ORCID: https://orcid.org/0000-0003-3725-1420)
- Mengxuan Yang (ORCID: https://orcid.org/0000-0003-4652-2472)
- Qibing Xie
- Geng Yin
- Ling Wei
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Sichuan University (CN)
- West China Medical Center of Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2025-12-26
- DOI
- https://doi.org/10.1002/art.70028
- Citations
- 2
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61