Innate immunity stimulation effects on biofluid/imaging biomarkers and cognition in a non‐human primate model of sporadic AD pathology
Our comprehensive NHP study will further validate this concept of immunomodulation as a safer approach to effectively ameliorate dementia-related pathology, particularly CAA, and support the potential clinical application of CpG-ODN 1018.
Authors
- Michele M. Mulholland (ORCID: https://orcid.org/0000-0003-1957-0436)
- Pramod N. Nehete (ORCID: https://orcid.org/0000-0002-2815-2677)
- William Donald Hopkins (ORCID: https://orcid.org/0000-0003-3480-1853)
- Akash G. Patel (ORCID: https://orcid.org/0000-0001-6282-9082)
- Ludovic Debure
- Henrieta Scholtzova (ORCID: https://orcid.org/0000-0003-0766-9463)
- Fengzhu Wang (ORCID: https://orcid.org/0009-0002-3758-6263)
- Lisa M. Pytka
- Noor Salaymeh
- Bharti P Nehete
- Jody Swain
- Thomas Wisniewski
- Brianna Ryckman
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- New York University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_106012
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00