Chemical‐Driven Clearance of Aβ and tau Aggregates by Orally Available Small Molecule Drug Candidate AS‐S603

AS-S603 is a first-in-class oral treatment for AD, uniquely targeting both Aβ and tau aggregates. It provides significant cognitive benefits in preclinical studies, suggesting its potential to alter disease progression. Clinical studies will validate its safety and efficacy, positioning AS-S603 as a transformative treatment for AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70859_100122
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Chemical‐Driven Clearance of Aβ and tau Aggregates by Orally Available Small Molecule Drug Candidate AS‐S603

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Chemical‐Driven Clearance of Aβ and tau Aggregates by Orally Available Small Molecule Drug Candidate AS‐S603

Y S. Kim, Hye‐Ju Kim, Yoon Sun Chun, Seong Jin Park, Seung Hoon Han, Seong Muk Kim, Hyemi Lee
article en

Abstract

AS-S603 is a first-in-class oral treatment for AD, uniquely targeting both Aβ and tau aggregates. It provides significant cognitive benefits in preclinical studies, suggesting its potential to alter disease progression. Clinical studies will validate its safety and efficacy, positioning AS-S603 as a transformative treatment for AD.

Alzheimer s & DementiaVol. 21(S5)
Incheon National University (KR), Yonsei University (KR), Solid (South Korea) (KR)
Openalex Percentile: Top 32%
Alzheimer's disease research and treatments
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