Comparison of Improvements in Quality of Life With Disease-Modifying Anti-rheumatic Drugs in Seropositive and Seronegative Rheumatoid Arthritis

Early initiation of csDMARDs in RA patients leads to significant improvement in QoL, regardless of serostatus. While both groups benefited similarly in HRQoL, seronegative patients experienced greater reductions in pain and disease activity, underscoring the efficacy of csDMARDs as an initial treatment strategy in RA management.

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Publication Details

Journal
Cureus
Published
2025-12-25
DOI
https://doi.org/10.7759/cureus.100094
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparison of Improvements in Quality of Life With Disease-Modifying Anti-rheumatic Drugs in Seropositive and Seronegative Rheumatoid Arthritis

M. A. Shalu, Avinash Muraleedharan, Ashish Yadav, Shweta Chaubey
Cureus
Rheumatoid Arthritis Research and Therapies
article

Comparison of Improvements in Quality of Life With Disease-Modifying Anti-rheumatic Drugs in Seropositive and Seronegative Rheumatoid Arthritis

M. A. Shalu, Avinash Muraleedharan, Ashish Yadav, Shweta Chaubey
article en

Abstract

Early initiation of csDMARDs in RA patients leads to significant improvement in QoL, regardless of serostatus. While both groups benefited similarly in HRQoL, seronegative patients experienced greater reductions in pain and disease activity, underscoring the efficacy of csDMARDs as an initial treatment strategy in RA management.

CureusVol. 17(12)
All India Institute of Medical Sciences Raipur (IN), Government Medical College (IN), Nagpur Institute of Technology (IN), Bangalore Baptist Hospital (IN), Central India Institute of Medical Sciences (IN), National Rehabilitation Center for Persons with Disabilities (JP), All India Institute of Medical Sciences, Nagpur (IN)
Openalex Percentile: Top 27%
Rheumatoid Arthritis Research and Therapies
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