Plasma Proteomic Associations with Alzheimer's Disease Endophenotypes
Multiple biological pathways and processes associated with cerebral β-amyloidosis, cognitive function, and other AD endophenotypes can be observed in plasma, some of which are likely influenced by peripheral factors. Therapeutic approaches targeting these pathways in the central nervous system or the periphery may modify AD risk or disease progression.
Authors
- Blaine R. Roberts
- Eric B. Dammer (ORCID: https://orcid.org/0000-0003-2947-7606)
- Cecelia Manzanares (ORCID: https://orcid.org/0000-0001-5266-0631)
- Douglas W. Beauregard
- Shijia Bian (ORCID: https://orcid.org/0000-0001-5314-0726)
- John Dwyer
- Richard C. Mohs
- Shiva Afshar
- Erik C.B. Johnson
- James J. Lah
- Allan I. Levey
- David A. A. Bennett
- Nicholas T. Seyfried
Institutions
- Emory University (US)
- Global Alzheimer's Platform Foundation (US)
- Rush University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_103553
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00