Cognitively defined AD dementia subgroups have different neuropathology findings in a community‐based autopsy cohort

We previously showed atrophy at AD diagnosis differed across subgroups. Here, patterns of neuropathology also appear to differ across subgroups. Further research is warranted on whether other natural history characteristics differ across cognitively defined subgroups.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70857_106090
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Cognitively defined AD dementia subgroups have different neuropathology findings in a community‐based autopsy cohort

Rod Walker, Marika Bogdani, Caitlin S. Latimer, Linda K. McEvoy et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Cognitively defined AD dementia subgroups have different neuropathology findings in a community‐based autopsy cohort

Rod Walker, Marika Bogdani, Caitlin S. Latimer, Linda K. McEvoy, Kelly Ehrlich, Connie Nakano, Seo‐Eun Choi, Paul K Crane, Shubhabrata Mukherjee, C. Dirk Keene, Michael L. Lee
article en

Abstract

We previously showed atrophy at AD diagnosis differed across subgroups. Here, patterns of neuropathology also appear to differ across subgroups. Further research is warranted on whether other natural history characteristics differ across cognitively defined subgroups.

Alzheimer s & DementiaVol. 21(S3)
Kaiser Permanente Washington Health Research Institute (US), University of Washington (US)
Quality Education
Openalex Percentile: Top 32%
Dementia and Cognitive Impairment Research
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