Depression is associated with higher t‐tau level in plasma: a report from the Framingham Heart Study
Depression was associated with higher t-tau levels in these cohorts. While current findings corroborate previous studies showing that depressive symptoms were not associated with plasma biomarkers of AD pathology, the positive association with t-tau level suggests the involvement of neuronal injury.
Authors
- Arash Salardini (ORCID: https://orcid.org/0000-0003-0193-6217)
- Vanessa M. Young (ORCID: https://orcid.org/0000-0003-4633-5052)
- Carlos Gaona (ORCID: https://orcid.org/0009-0000-9425-8907)
- A. Ballano Ruiz
- Antonio L. Teixeira
- Rebecca Bernal
- Jayandra J. Himali
- Crystal Wiedner
- Sudha Seshadri
- Alexa S Beiser
Institutions
- Boston University (US)
- The University of Texas at San Antonio Health Science Center (US)
- Universitat Internacional de Catalunya (ES)
- Biomedical Research Networking Center on Neurodegenerative Diseases (ES)
- Institute for Neurodegenerative Disorders (US)
- The University of Texas at San Antonio (US)
- Arizona State University (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_103034
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00