Repurposed Drug Prioritisation Pipeline for an Alzheimer’s Disease Multi‐arm Platform Trial
We present a practical approach to prioritising repurposed drugs to evaluate in the context of clinical AD. We would like to thank our patient and public contributors and the wider investigator team.
Authors
- Gordon Wilcock (ORCID: https://orcid.org/0000-0003-0163-3021)
- Eric Karran (ORCID: https://orcid.org/0000-0002-6782-5213)
- Benjamin R. Underwood (ORCID: https://orcid.org/0000-0003-3427-9487)
- Leah Mursaleen
- O'Brien John Tiernan
- Suzanne Reeves (ORCID: https://orcid.org/0000-0001-8053-7024)
- Cecilia Olivares
- Sabahat Iqbal (ORCID: https://orcid.org/0000-0001-7658-6384)
- Ross Dunne (ORCID: https://orcid.org/0000-0003-2046-6193)
- James R. Carpenter (ORCID: https://orcid.org/0000-0003-3890-6206)
- Alastair D. Reith (ORCID: https://orcid.org/0000-0001-5092-0604)
- Fiona Ducotterd (ORCID: https://orcid.org/0009-0000-6064-9088)
- Laura Rizzo (ORCID: https://orcid.org/0009-0007-8716-863X)
- CS Wong
- Malhotra Paresh
- Vanessa Raymont
- Lon S. S Schneider
- Rik Vandenberghe
- Jeffrey L. Cummings
- Catherine J. Mummery
- Thomas D Parker
Institutions
- University of Southern California (US)
- Allen Institute for Brain Science (US)
- University of Nevada, Las Vegas (US)
- Imperial College Healthcare NHS Trust (GB)
- Greater Manchester Mental Health NHS Foundation Trust (GB)
- Manchester Academic Health Science Centre (GB)
- University of Manchester (GB)
- University of Oxford (GB)
- Cambridge School (PT)
- UK Dementia Research Institute (GB)
- Alzheimer’s Research UK (GB)
- Cambridgeshire and Peterborough NHS Foundation Trust (GB)
- Science Oxford (GB)
- VIB-KU Leuven Center for Brain & Disease Research (BE)
- NIHR Research Delivery Network (GB)
- Accenture (United Kingdom) (GB)
- Dementias Platform UK (GB)
- University College London (GB)
- Imperial College London (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70859_102227
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00