Performance of Cognitive Screening Tests for Alzheimer's Disease Pathology Defined by Plasma <i>p</i> ‐tau217: A Prospective Cohort Study in Early Dementia Patients at King Chulalongkorn Memorial Hospital, Thailand
In our cohort, a MoCA-Thai cut-off of ≤21 and a MoCA-MIS cut-off of ≤6 provided the best optimal sensitivity and specificity for detecting AD pathology. These findings support the integration of cognitive screening tests with plasma biomarkers to enhance early AD detection in clinical settings in Thailand, where access to advanced diagnostics is limited.
Authors
- Yuthachai Sarutikriangkri
- Prawit Oangkhana (ORCID: https://orcid.org/0000-0002-7644-4236)
- Watayuth Luechaipanit
- Akarin Hiransuthikul (ORCID: https://orcid.org/0000-0003-1906-8171)
- Thanakit Pongpitakmetha (ORCID: https://orcid.org/0000-0002-8338-4649)
- Yuttachai Likitjaroen (ORCID: https://orcid.org/0009-0009-7488-325X)
- Adipa Chongsuksantikul
- Poosanu Thanapornsangsuth (ORCID: https://orcid.org/0000-0002-1317-9404)
- Thanaporn Haethaisong
- Tara Rak‐Areekul
Institutions
- Thai Red Cross Society (TH)
- Chulalongkorn University (TH)
- King Chulalongkorn Memorial Hospital (TH)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70857_107090
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00